Statistics for the Luria-Delbr\"uck distribution

  title={Statistics for the Luria-Delbr\"uck distribution},
  author={Agn{\`e}s Hamon and Bernard Ycart},
The Luria-Delbrück distribution is a classical model of mutations in cell kinetics. It is obtained as a limit when the probability of mutation tends to zero and the number of divisions to infinity. It can be interpreted as a compound Poisson distribution (for the number of mutations) of exponential mixtures (for the developing time of mutant clones) of geometric distributions (for the number of cells produced by a mutant clone in a given time). The probabilistic interpretation, and a rigourous… CONTINUE READING
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