Statistical simulations to estimate motion-inclusive dose-volume histograms for prediction of rectal morbidity following radiotherapy.

@article{Thor2013StatisticalST,
  title={Statistical simulations to estimate motion-inclusive dose-volume histograms for prediction of rectal morbidity following radiotherapy.},
  author={Maria Thor and Aditya Apte and Joseph O. Deasy and Ludvig P. Muren},
  journal={Acta oncologica},
  year={2013},
  volume={52 3},
  pages={666-75}
}
BACKGROUND AND PURPOSE Internal organ motion over a course of radiotherapy (RT) leads to uncertainties in the actual delivered dose distributions. In studies predicting RT morbidity, the single estimate of the delivered dose provided by the treatment planning computed tomography (pCT) is typically assumed to be representative of the dose distribution throughout the course of RT. In this paper, a simple model for describing organ motion is introduced, and is associated to late rectal morbidity… CONTINUE READING