Statistical properties of limit of detection test statistics.

@article{Montville2003StatisticalPO,
  title={Statistical properties of limit of detection test statistics.},
  author={Daniel Montville and Edward Voigtman},
  journal={Talanta},
  year={2003},
  volume={59 3},
  pages={461-76}
}
There are a number of possible ways to define the instrumental limit of detection (LOD) figure of merit and in the present work we define four such sample test statistics and derive their probability density functions (PDFs). Although the derived PDFs were found to be irreducible integrals, they are easily evaluated via numerical integration and can be used to obtain expectation values, population precisions and confidence intervals. Monte Carlo simulation methods were used to prepare… CONTINUE READING