Statistical methods for gene set co-expression analysis

@inproceedings{Choi2009StatisticalMF,
  title={Statistical methods for gene set co-expression analysis},
  author={YounJeong Choi and Christina Kendziorski},
  booktitle={Bioinformatics},
  year={2009}
}
MOTIVATION The power of a microarray experiment derives from the identification of genes differentially regulated across biological conditions. To date, differential regulation is most often taken to mean differential expression, and a number of useful methods for identifying differentially expressed (DE) genes or gene sets are available. However, such methods are not able to identify many relevant classes of differentially regulated genes. One important example concerns differentially co… CONTINUE READING
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