Statistical methods for assessing the influence of study characteristics on treatment effects in 'meta-epidemiological' research.

Abstract

Biases in systematic reviews and meta-analyses may be examined in 'meta-epidemiological' studies, in which the influence of trial characteristics such as measures of study quality on treatment effect estimates is explored. Published studies to date have analysed data from collections of meta-analyses with binary outcomes, using logistic regression models… (More)

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