Statistical methodology: I. Incorporating the prevalence of disease into the sample size calculation for sensitivity and specificity.

  • Nancy M. Buderer
  • Published 1996 in
    Academic emergency medicine : official journal of…


Careful consideration of statistical issues related to the choice of a sample size is critical for achieving meaningful results in research studies designed to evaluate diagnostic tests. When assessing the ability of a diagnostic test to screen for disease, the parameters sensitivity, specificity, and predictive values are of interest. Study sample size… (More)


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