Statistical media optimization for growth and PHB production from methanol by a methylotrophic bacterium.

@article{MokhtariHosseini2009StatisticalMO,
  title={Statistical media optimization for growth and PHB production from methanol by a methylotrophic bacterium.},
  author={Zahra B Mokhtari-Hosseini and Ebrahim Vasheghani-Farahani and Ali Heidarzadeh-Vazifekhoran and Seyed Abbas Shojaosadati and Ramin Karimzadeh and Kianoush Khosravi Darani},
  journal={Bioresource technology},
  year={2009},
  volume={100 8},
  pages={2436-43}
}
Media components were optimized by statistical design for cell growth and PHB production of Methylobacterium extorquens DSMZ 1340. Four important components of growth media were optimized by central composite design. The growth increased from an OD=1.35 for Choi medium as control to an OD=2.15 for optimal medium. Then media components for PHB production were optimized. Optimization of five important factors was conducted by response surface method. The optimal composition of PHB production… CONTINUE READING