Statistical Significance of Precisely Repeated Intracellular Synaptic Patterns

@article{Ikegaya2008StatisticalSO,
  title={Statistical Significance of Precisely Repeated Intracellular Synaptic Patterns},
  author={Yuji Ikegaya and Wataru Matsumoto and Huei-Yu Chiou and Rafael Yuste and Gloster Aaron},
  journal={PLoS ONE},
  year={2008},
  volume={3},
  pages={883 - 898}
}
Can neuronal networks produce patterns of activity with millisecond accuracy? It may seem unlikely, considering the probabilistic nature of synaptic transmission. However, some theories of brain function predict that such precision is feasible and can emerge from the non-linearity of the action potential generation in circuits of connected neurons. Several studies have presented evidence for and against this hypothesis. Our earlier work supported the precision hypothesis, based on results… CONTINUE READING

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