Statistical Mechanics of Semiflexible Polymers: Theory and Experiment

@article{Frey1998StatisticalMO,
  title={Statistical Mechanics of Semiflexible Polymers: Theory and Experiment},
  author={Erwin Frey and Klaus Kroy and Jan Wilhelm and Erich. Sackmann},
  journal={arXiv: Soft Condensed Matter},
  year={1998},
  pages={103-119}
}
Living cells are soft bodies of a characteristic form, but endowed with a capacity for a steady turnover of their structures. Both of these material properties, i. e. recovery of the shape after an external stress has been imposed and dynamic structural reorganization, are essential for many cellular phenomena. Examples are active intracellular transport, cell growth ard division, and directed movement of cells. The structural element responsible for the extraordinary mechanical and dynamical… 

Figures from this paper

Simulation of self-assembly and mechanics of transiently crosslinked, semiflexible biopolymer networks
Finite element simulations of biopolymer networks can reveal key properties of biological cells. Having developed a network model of polymer fibers and crosslinkers, accounting for their Brownian
Elastically coupled molecular motors
TLDR
It is found that for a backbone flexibility exceeding a characteristic value, the ability of motors to produce force reduces as compared to rigidly coupled motors, while the maximum velocity remains unchanged.
Collective Dynamics of Molecular Motors
TLDR
The binding of dimeric kinesin motors to microtubules in the absence of ATP is studied and the equilibrium state as well as relaxation kinetics are discussed.
Actin filaments and networks under force: A computational study
TLDR
This work investigates how forces affect actin at the filament and network length scales and explores how actin networks respond to large external forces, and develops a constant-stress framework to apply large forces on soft but strongly nonlinear materials.
Brownian motion: a paradigm of soft matter and biological physics
This is a pedagogical introduction to Brownian motion on the occasion of the 100th anniversary of Einstein's 1905 paper on the subject. After briefly reviewing Einstein's work in a contemporary
Statische und dynamische Lichtstreuung an Lösungen von Aktinfilamenten
Unter geeigneten Bedingungen polymerisiert das Zytoskelettprotein Aktin zu Filamenten. Aufgrund der auserordentlichen Konturlangen dieser Polymere (bis in den 100 µm Bereich) sind Losungen dieser

References

SHOWING 1-10 OF 36 REFERENCES
Theoretical estimates of mechanical properties of the endothelial cell cytoskeleton.
Trapping and wiggling: elastohydrodynamics of driven microfilaments.
Direct imaging of reptation for semiflexible actin filaments
TLDR
Video microscopy of fluorescently labelled single, semiflexible filaments of actin in a solution of unlabelled actin filaments finds that the chain self-diffusion coefficient decreases approximately linearly as the filament length increases, in agreement with the reptation model.
Mechanical properties of cytoskeletal polymers.
  • P. Janmey
  • Biology, Chemistry
    Current opinion in cell biology
  • 1991
Mechanical perturbation elicits a phenotypic difference between Dictyostelium wild-type cells and cytoskeletal mutants.
Elasticity of semiflexible biopolymer networks.
TLDR
This model can explain a number of elastic properties of cross-linked gels and sterically entangled solutions of semiflexible biopolymers such as F-actin in vitro, including the concentration dependence of the storage modulus and yield strain.
Flexural rigidity of microtubules and actin filaments measured from thermal fluctuations in shape
TLDR
The first accurate measurements of the flexural rigidity of microtubules are reported, showing that a microtubule is rigid over cellular dimensions and is expected to be almost inextensible.
Dynamics and rheology of actin solutions
TLDR
The macroscopic storage modulus is deduced and it is shown that over a certain frequency range semiflexible polymers show a novel variation in the shear modulus; the mechanism should be distinguished from Rouse behavior in solutions of flexible polymers.
Structure and mobility of actin filaments as measured by quasielastic light scattering, viscometry, and electron microscopy.
TLDR
The results suggest that the rheology of actin filaments can be accounted for by steric restraints and the length of these filaments in some cell types is such that these steric constraints are significant and could produce large changes in physical properties with small changes in filament length.
Cross-linker dynamics determine the mechanical properties of actin gels.
...
1
2
3
4
...