Statistical Issues in Modeling Chronic Disease in Cohort Studies

@inproceedings{Cook2014StatisticalII,
  title={Statistical Issues in Modeling Chronic Disease in Cohort Studies},
  author={Richard J. Cook},
  year={2014}
}
Observational cohort studies of individuals with chronic disease provide information on rates of disease progression, the effect of fixed and time-varying risk factors, and the extent of heterogeneity in the course of disease. Analysis of this information is often facilitated by the use of multistate models with intensity functions governing transition between disease states. We discuss modeling and analysis issues for such models when individuals are observed intermittently. Frameworks for… CONTINUE READING
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