Statistical Decision Properties of Imprecise Trials Assessing Covid-19 Drugs

  title={Statistical Decision Properties of Imprecise Trials Assessing Covid-19 Drugs},
  author={Charles F. Manski and Aleksey Tetenov},
  journal={NBER Working Paper Series},
As the COVID-19 pandemic progresses, researchers are reporting findings of randomized trials comparing standard care with care augmented by experimental drugs. The trials have small sample sizes, so estimates of treatment effects are imprecise. Seeing imprecision, clinicians reading research articles may find it difficult to decide when to treat patients with experimental drugs. Whatever decision criterion one uses, there is always some probability that random variation in trial outcomes will… 

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