Statistical Assessment of Crosstalk Enrichment between Gene Groups in Biological Networks

@inproceedings{McCormack2013StatisticalAO,
  title={Statistical Assessment of Crosstalk Enrichment between Gene Groups in Biological Networks},
  author={Theodore McCormack and Oliver Frings and Andrey Alexeyenko and Erik L. L. Sonnhammer},
  booktitle={PloS one},
  year={2013}
}
MOTIVATION Analyzing groups of functionally coupled genes or proteins in the context of global interaction networks has become an important aspect of bioinformatic investigations. Assessing the statistical significance of crosstalk enrichment between or within groups of genes can be a valuable tool for functional annotation of experimental gene sets. RESULTS Here we present CrossTalkZ, a statistical method and software to assess the significance of crosstalk enrichment between pairs of gene… CONTINUE READING
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KEGG: Kyoto Encyclopedia of Genes and Genomes

Nucleic Acids Research • 2000
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