Statins in homozygous familial hypercholesterolemia
@article{Marais2002StatinsIH, title={Statins in homozygous familial hypercholesterolemia}, author={Adrian D Marais and Dirk Jacobus Blom and Jean Catherine Firth}, journal={Current Atherosclerosis Reports}, year={2002}, volume={4}, pages={19-25} }
Homozygous familial hypercholesterolemia is a rare disorder resulting in severe premature atherosclerosis. Drug therapy was previously viewed as inadequate for control of the dyslipidemia, so portacaval shunting, plasmapheresis, and liver transplantation were undertaken to treat this condition. Despite these drastic measures, additional cholesterol-lowering treatment may still be required. Furthermore, there is a need for pharmacologic control until additional measures can be undertaken. The…
38 Citations
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