Statins but not angiotensin-converting enzyme inhibitors delay progression of aortic stenosis.

  title={Statins but not angiotensin-converting enzyme inhibitors delay progression of aortic stenosis.},
  author={Raphael A Rosenhek and Florian Rader and Nicole Loho and Harald Gabriel and Maria Heger and Ursula Klaar and Michael Schemper and Thomas Binder and Gerald Maurer and Helmut Baumgartner},
  volume={110 10},
BACKGROUND Recently, statins and angiotensin-converting enzyme inhibitors (ACEIs) have been shown to slow aortic valve calcium accumulation. Although several studies also suggest that statins may reduce the hemodynamic progression of aortic stenosis (AS), no data are available for ACEIs or the combination of both. METHODS AND RESULTS A total of 211 consecutive patients (aged 70+/-10 years, 104 females) with native AS, defined by a peak velocity >2.5 m/s (valve area 0.84+/-0.23 cm(2), mean… CONTINUE READING
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Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, doubleblind, placebo-controlled, multicentre trial (the EUROPA study)

  • KM Fox
  • Lancet
  • 2003

Angiotensin converting enzyme inhibitor use is associated with a decreased rate of aortic valve calcium accumulation

  • MT Caulfield, MJ Budoff, J Takasu
  • Circulation. 2002;106(suppl II):II-640. Abstract
  • 2002

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