Statins are detrimental to human placental development and function; use of statins during early pregnancy is inadvisable

@inproceedings{Forbes2008StatinsAD,
  title={Statins are detrimental to human placental development and function; use of statins during early pregnancy is inadvisable},
  author={Karen Forbes and Lucy M Hurst and J. Martin Gibson and John D Aplin and Melissa Westwood},
  booktitle={Journal of cellular and molecular medicine},
  year={2008}
}
is one of the major healthcare problems of the Western world. Affected individuals are often treated with statins (HMG CoA reductase inhibitors) to reduce circulating cholesterol levels and the risk of developing cardiovascular disease [1]; given the evolving demographic profile of these conditions, such drugs are increasingly prescribed to women of reproductive age. Cholesterol is essential for normal foetal development and therefore the use of lipid-lowering drugs, including statins, is… CONTINUE READING