Statins and Breast Cancer: Future Directions in Chemoprevention.

  title={Statins and Breast Cancer: Future Directions in Chemoprevention.},
  author={Cesar A Santa-Maria and Vered Stearns},
  journal={Current breast cancer reports},
  volume={5 3},
Given the high incidence, morbidity and mortality associated with breast cancer, developing effective chemopreventive strategies is crucial. Clinicians must carefully identify both populations at risk who would benefit from chemoprevention, and interventions that are effective and safe. Tamoxifen and raloxifene, the two agents approved for breast cancer chemoprevention, and third generation aromatase inhibitors reduce only the incidence of hormone receptor-positive tumors. 3-hydroxy-3-methyl… CONTINUE READING