Statins: panacea for sepsis?

@article{Terblanche2006StatinsPF,
  title={Statins: panacea for sepsis?},
  author={Marius Terblanche and Yaniv Almog and Robert S Rosenson and Terry S Smith and Daniel G. Hackam},
  journal={The Lancet. Infectious diseases},
  year={2006},
  volume={6 4},
  pages={
          242-8
        }
}
Sepsis occurs when the immune system responds to a localised infection at a systemic level, thereby causing tissue damage and organ dysfunction. Statins have proven health benefits in many diseases involving vascular inflammation and injury. Recent animal data suggest that the administration of a statin before a sepsis-inducing insult reduces morbidity and improves survival. The immunomodulatory and anti-inflammatory effects of statins, collectively referred to as pleiotropic effects, lend… CONTINUE READING

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