Statin therapy is associated with improved pathologic response to neoadjuvant chemoradiation in rectal cancer.

@article{Mace2013StatinTI,
  title={Statin therapy is associated with improved pathologic response to neoadjuvant chemoradiation in rectal cancer.},
  author={Adam G Mace and Gerald A. Gantt and Marek Skacel and Rish K Pai and Jeff P. Hammel and Matthew F Kalady},
  journal={Diseases of the colon and rectum},
  year={2013},
  volume={56 11},
  pages={1217-27}
}
BACKGROUND Achieving a pathologic complete response to neoadjuvant chemoradiation improves prognosis in rectal cancer. Statin therapy has been shown to enhance the impact of treatment in several malignancies, but little is known regarding the impact on rectal cancer response to neoadjuvant chemoradiation. OBJECTIVE The purpose of this study was to determine whether statin use during neoadjuvant chemoradiation improves pathologic response in rectal cancer. DESIGN This was a retrospective… CONTINUE READING

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