Statin therapy decreases the risk of osteonecrosis in patients receiving steroids.

Abstract

Osteonecrosis is a devastating complication of systemic steroid use. Prolonged steroid use produces a hyperlipidemic state in most patients and puts them at risk for osteoporosis and osteonecrosis. The fat content within the femoral head increases, resulting in increased intracortical pressure that may lead to sinusoidal collapse and osteonecrosis. Statins… (More)

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Cite this paper

@article{Pritchett2001StatinTD, title={Statin therapy decreases the risk of osteonecrosis in patients receiving steroids.}, author={James W. Pritchett}, journal={Clinical orthopaedics and related research}, year={2001}, volume={386}, pages={173-8} }