Statin therapy attenuates growth and malignant potential of human esophageal adenocarcinoma cells.


OBJECTIVES Esophageal adenocarcinoma is an aggressive malignancy generally diagnosed after metastatic spread and currently lacks effective medical therapy. Expression of intracellular adhesion molecule-1 (ICAM-1) is an adverse prognostic indicator in various human tumor cells and contributes significantly to their metastatic potential. Statin therapy… (More)
DOI: 10.1016/j.jtcvs.2011.08.004


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