Statin therapy and long-term adverse limb outcomes in patients with peripheral artery disease: insights from the REACH registry.

@article{Kumbhani2014StatinTA,
  title={Statin therapy and long-term adverse limb outcomes in patients with peripheral artery disease: insights from the REACH registry.},
  author={Dharam Jaydeep Kumbhani and Philippe Gabriel Steg and Christopher Paul Cannon and Kim Allan Eagle and Sidney C. Smith and Shinichi Goto and E Magnus Ohman and Yedid Elbez and Piyamitr Sritara and Iris Baumgartner and Subhash Banerjee and Mark A. Creager and Deepak L Bhatt},
  journal={European heart journal},
  year={2014},
  volume={35 41},
  pages={2864-72}
}
AIMS Due to a high burden of systemic cardiovascular events, current guidelines recommend the use of statins in all patients with peripheral artery disease (PAD). We sought to study the impact of statin use on limb prognosis in patients with symptomatic PAD enrolled in the international REACH registry. METHODS Statin use was assessed at study enrolment, as well as a time-varying covariate. Rates of the primary adverse limb outcome (worsening claudication/new episode of critical limb ischaemia… CONTINUE READING
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