State of the art. Cellular and molecular mechanisms of alveolar destruction in emphysema: an evolutionary perspective.

Abstract

Emphysema consists of a unique pattern of alveolar destruction, resulting in marked airspace enlargement with reduction of alveolar capillary exchange area. Classical concepts of the pathogenesis of emphysema have relied on the paradigm set by the inflammation and protease/antiprotease imbalance. We propose herein that cigarette smoke constitutes an… (More)

Topics

Cite this paper

@article{Tuder2006StateOT, title={State of the art. Cellular and molecular mechanisms of alveolar destruction in emphysema: an evolutionary perspective.}, author={Rubin M. Tuder and Toshinori Yoshida and Wadih Arap and Renata Pasqualini and Irina Petrache}, journal={Proceedings of the American Thoracic Society}, year={2006}, volume={3 6}, pages={503-10} }