State of the Art. A structural and functional assessment of the lung via multidetector-row computed tomography: phenotyping chronic obstructive pulmonary disease.

@article{Hoffman2006StateOT,
  title={State of the Art. A structural and functional assessment of the lung via multidetector-row computed tomography: phenotyping chronic obstructive pulmonary disease.},
  author={Eric A. Hoffman and Brett Simon and Geoffrey McLennan},
  journal={Proceedings of the American Thoracic Society},
  year={2006},
  volume={3 6},
  pages={519-32}
}
With advances in multidetector-row computed tomography (MDCT), it is now possible to image the lung in 10 s or less and accurately extract the lungs, lobes, and airway tree to the fifth- through seventh-generation bronchi and to regionally characterize lung density, texture, ventilation, and perfusion. These methods are now being used to phenotype the lung in health and disease and to gain insights into the etiology of pathologic processes. This article outlines the application of these… CONTINUE READING
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