State of belief, subjective certainty and bliss as a product of cortical dysfunction

@article{Picard2013StateOB,
  title={State of belief, subjective certainty and bliss as a product of cortical dysfunction},
  author={F. Picard},
  journal={Cortex},
  year={2013},
  volume={49},
  pages={2494-2500}
}
  • F. Picard
  • Published 2013
  • Psychology, Medicine
  • Cortex
INTRODUCTION Ecstatic seizures are focal epileptic seizures which are fascinating from a phenotypical point of view as they include intense positive affect, feelings of heightened self-awareness and enhanced well-being. They have been previously suggested to arise in the anterior insular cortex, although strong arguments are still lacking. METHODS We describe the cases of two new patients with ecstatic seizures. Their evaluation included a careful history, encouraging the patient to provide… Expand
View on Elsevier
doi.org
48 Citations
Highly Influential Citations
2
Background Citations
19
Methods Citations
1
Results Citations
1

48 Citations

Citation Type

Citation Type

Ecstatic Epileptic Seizures - the Role of the Insula in Altered Self-Awareness
Ecstatic auras are a rare but compelling epileptic entity. During the first seconds of the seizure, ecstatic auras provoke feelings of well-being, intense serenity, bliss, and enhanced… Expand
Ictal alterations of consciousness during ecstatic seizures
TLDR
This review will summarize previous patient reports and recap how insular functioning may be involved in the phenomenon of ecstatic seizures and relate these hypotheses to the results from research on meditation and effects of drug abuse. Expand
Ecstatic Epileptic Seizures: A Glimpse into the Multiple Roles of the Insula
TLDR
The role of the multiple sensory, autonomic, affective, and cognitive functions of the insular cortex, which are integrated into the creation of self-awareness, are summarized and it is suggested how this system may become dysfunctional on several levels during ecstatic aura. Expand
The role of the dorsal anterior insula in ecstatic sensation revealed by direct electrical brain stimulation
BACKGROUND An ecstatic phenomenon is an altered state of consciousness with a sense of "hyper-reality", and a complete present-moment awareness with a feeling of union with the Universe. A better… Expand
[Dostoyevsky's epilepsy in the light of recent neurobiological data].
TLDR
According to new electrophysiology and imaging techniques ecstatic seizures--including the seizure onset of Dostoyevsky--could rather be connected to the insular cortex. Expand
Validating New Technologies to Treat Depression, Pain and the Feeling of Sentient Beings: A Reply to “Neuroscience for the Soul”
The primary assumption of Neuroscience is that all experiences are strongly correlated with or caused by the specifics of brain structures and their particular dynamics. The profound experiences… Expand
Predictions, perception, and a sense of self
TLDR
It is proposed that the predictive or inferential perspective on brain function offers novel insights into brain diseases. Expand
Ecstatic and gelastic seizures relate to the hypothalamus
TLDR
It is speclate patients with ecstatic seizures may have an ictal activation of neuronal networks that involves the insula, a location that has not previously been described in ecstatic seizures. Expand
The possible role of the insula in the epilepsy and the gambling disorder of Fyodor Dostoyevsky
TLDR
It is hypothesized that the three common gambling-related cognitive distortions can be all attributed to the impairment of the anterior insular risk prediction–risk prediction error coding system. Expand
Role of the Insular Cortex in Emotional Awareness
New studies keep drawing attention to the role of the insular cortex in emotional awareness. Emotional awareness is necessary to achieve and maintain mental health and social well-being. This chapter… Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 46 REFERENCES
Insular cortex activation in a patient with "sensed presence"/ecstatic seizures
TLDR
The present findings support the proposal that ecstatic seizures or "sensed presence" auras can originate from the left anterior insula, a region that has been suggested to engender self-awareness associated with positive feelings. Expand
Ecstatic epileptic seizures: A potential window on the neural basis for human self-awareness
TLDR
It is proposed here that the descriptions by patients, together with the neurophysiological and neuroradiological evidence, support a theoretical framework for understanding ecstatic states based on hyperactivation of the anterior insula, rather than the temporal lobe. Expand
Clinical manifestations of insular lobe seizures: a stereo-electroencephalographic study
TLDR
Observation of this clinical sequence at the onset of seizures on video-EEG recordings in TLE patients strongly suggests that the seizure-onset zone is located not in the temporal but in the insular lobe; recording directly from theinsular cortex should occur before making any decision regarding epilepsy surgery. Expand
Ictal Pleasant Sensations: Cerebral Localization and Lateralization
TLDR
Ictal happiness is a localizing sign pointing to the ictal involvement of temporal mesiobasal areas in patients with focal epilepsies, and it is found that the origin of the focal epileptic activity was found in the temporal lobe. Expand
Disproportionate Alterations in the Anterior and Posterior Insular Cortices in Obsessive–Compulsive Disorder
TLDR
The results suggest the presence of unbalanced anterior and posterior insular volumetric abnormalities in unmedicated OCD patients and emphasize the distinct role of the insular cortex in different OC symptoms, which are proposed to influence the modulation of interoceptive processing in OCD patients with different symptoms. Expand
Representation of pain and somatic sensation in the human insula: a study of responses to direct electrical cortical stimulation.
TLDR
It is found that painful and non-painful somaesthetic representations in the human insula overlap, and lateralization in the right hemisphere of sites where painful sensations were evoked is coherent with the hypothesis of a preponderant role of this hemisphere in species survival. Expand
Anterior insular volume is larger in patients with obsessive–compulsive disorder
TLDR
This is the first volumetric MRI study to separately investigate the anterior and posterior insular cortex volumes in non-medicated patients with OCD and the results suggest that the anteriorinsular cortex may be related to the pathophysiology of OCD. Expand
Activation of Anterior Insula during Self-Reflection
TLDR
The results provide further evidence for the specific recruitment of anterior MPFC and ACC regions for self-related processing, and highlight a role for the insula in self-reflection. Expand
Functional neuroanatomy of aversion and its anticipation
TLDR
Results show that anticipation of aversion recruits key brain regions that respond to aversion, thereby potentially enhancing adaptive responses to aversive events. Expand
Anterior insula reactivity during certain decisions is associated with neuroticism.
TLDR
It is suggested that increasing levels of neuroticism modulate neural activation in such a way that the brain interprets certainty as uncertain. Expand
...
1
2
3
4
5
...