State-dependent respiratory depression elicited by stimulation of the orbital frontal cortex.


The effect of electrical stimulation of the orbital frontal cortex on respiration was studied in unanesthetized, freely moving cats across sleep-waking states. Single trains of forty 300-microA, 0.5-ms, constant-current pulses at 60 Hz were delivered to the orbital frontal cortex at four points in the respiratory cycle. Stimuli delivered during expiration… (More)


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