State-Dependent Heterogeneity in Synaptic Depression between Pyramidal Cell Pairs

@article{Montgomery2002StateDependentHI,
  title={State-Dependent Heterogeneity in Synaptic Depression between Pyramidal Cell Pairs},
  author={Johanna M Montgomery and Daniel V. Madison},
  journal={Neuron},
  year={2002},
  volume={33},
  pages={765-777}
}
Paired recordings between CA3 pyramidal neurons were used to study the properties of synaptic plasticity in active and silent synapses. Synaptic depression is accompanied by decreases in both AMPAR and NMDAR function. The mechanisms of synaptic depression, and the potential to undergo activity-dependent plastic changes in efficacy, differ depending on whether a synapse is active, recently silent, or potentiated. These results suggest that silent and active synapses represent distinct synaptic… CONTINUE READING
91 Citations
73 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 91 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 73 references

Nicoll, synaptic modification mediates long-term potentiation in the hippoR.A., Malenka

  • R. C. Carroll, E. C. Beattie, H. Xia, C. Luscher, Y. Altschuler
  • R.C., and von Zastrow, M. (1999a). Dynamin-depen…
  • 1999
Highly Influential
8 Excerpts

Long - term decordings reveal allsilent synaptic connections and the postsynaptic pression in the hippocampal CA 1 region is associated with equalexpression of long - term potentiation

  • M. Y. Xiao, H. Wigstrom, B. Gustafsson
  • Neuron
  • 1994
Highly Influential
5 Excerpts

lates hippocampal long-term depression

  • R. C. Carroll, E. C. Beattie, M. von Zastrow, R. C. Malenka
  • Proc. Natl. Acad. Sci. USA
  • 2001
Highly Influential
6 Excerpts

in synaptic transmission and plasticity

  • R. Shigemoto, A. Kinoshita, +7 authors N. Mizuno
  • Neuron
  • 1997
Highly Influential
1 Excerpt

Similar Papers

Loading similar papers…