StartReact Effects Support Different Pathophysiological Mechanisms Underlying Freezing of Gait and Postural Instability in Parkinson’s Disease

@inproceedings{Nonnekes2015StartReactES,
  title={StartReact Effects Support Different Pathophysiological Mechanisms Underlying Freezing of Gait and Postural Instability in Parkinson’s Disease},
  author={Jorik Nonnekes and Digna de Kam and Lars B. Oude Nijhuis and Karin van Geel and Bastiaan R. Bloem and Alexander C Geurts and Vivian Weerdesteyn},
  booktitle={PloS one},
  year={2015}
}
INTRODUCTION The pathophysiology underlying postural instability in Parkinson's disease is poorly understood. The frequent co-existence with freezing of gait raises the possibility of shared pathophysiology. There is evidence that dysfunction of brainstem structures contribute to freezing of gait. Here, we evaluated whether dysfunction of these structures contributes to postural instability as well. Brainstem function was assessed by studying the StartReact effect (acceleration of latencies by… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 62 references

Similar Papers

Loading similar papers…