Staphyloxanthin plays a role in the fitness of Staphylococcus aureus and its ability to cope with oxidative stress.

@article{Clauditz2006StaphyloxanthinPA,
  title={Staphyloxanthin plays a role in the fitness of Staphylococcus aureus and its ability to cope with oxidative stress.},
  author={Alexandra Clauditz and Alexandra Resch and K Wieland and Andreas Peschel and Friedrich G{\"o}tz},
  journal={Infection and immunity},
  year={2006},
  volume={74 8},
  pages={4950-3}
}
Staphyloxanthin is a membrane-bound carotenoid of Staphylococcus aureus. Here we studied the interaction of staphyloxanthin with reactive oxygen substances (ROS) and showed by comparative analysis of the wild type (WT) and an isogenic crtM mutant that the WT is more resistant to hydrogen peroxide, superoxide radical, hydroxyl radical, hypochloride, and neutrophil killing. 

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Organisation und Genexpression der Carotinoid-Biosynthesegene aus Staphylococcus aureus Newman und Untersuchungen zur Funktion von Staphyloxanthin

  • K. B. Wieland
  • Ph.D. thesis
  • 1999

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