Staphylococcus aureus requires cardiolipin for survival under conditions of high salinity

  title={Staphylococcus aureus requires cardiolipin for survival under conditions of high salinity},
  author={Melody M Tsai and Ryosuke L. Ohniwa and Yusuke Kato and Sayaka L Takeshita and Toshiko Ohta and Shinji Saito and Hideo Hayashi and Kazuya Morikawa},
  booktitle={BMC Microbiology},
The ability of staphylococci to grow in a wide range of salt concentrations is well documented. In this study, we aimed to clarify the role of cardiolipin (CL) in the adaptation of Staphylococcus aureus to high salinity. Using an improved extraction method, the analysis of phospholipid composition suggested that CL levels increased slightly toward stationary phase, but that this was not induced by high salinity. Deletion of the two CL synthase genes, SA1155 (cls1) and SA1891 (cls2), abolished… CONTINUE READING

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  • Nat Rev Microbiol
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