Staphylococcus aureus enterotoxins A− and B: binding to the enterocyte brush border and uptake by perturbation of the apical endocytic membrane traffic

@article{Danielsen2012StaphylococcusAE,
  title={Staphylococcus aureus enterotoxins A− and B: binding to the enterocyte brush border and uptake by perturbation of the apical endocytic membrane traffic},
  author={Erik Danielsen and Gert Helge Hansen and Edda R{\'o}s Karlsd{\'o}ttir},
  journal={Histochemistry and Cell Biology},
  year={2012},
  volume={139},
  pages={513-524}
}
Enterotoxins of Staphylococcus aureus are among the most common causes of food poisoning. Acting as superantigens they intoxicate the organism by causing a massive uncontrolled T cell activation that ultimately may lead to toxic shock and death. In contrast to our detailed knowledge regarding their interaction with the immune system, little is known about how they penetrate the epithelial barrier to gain access to their targets. We therefore studied the uptake of two staphylococcal enterotoxins… CONTINUE READING

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