Staphylococcus aureus competence genes: mapping of the SigH, ComK1 and ComK2 regulons by transcriptome sequencing

@article{Fagerlund2014StaphylococcusAC,
  title={Staphylococcus aureus competence genes: mapping of the SigH, ComK1 and ComK2 regulons by transcriptome sequencing},
  author={Annette Fagerlund and P. Granum and L. H{\aa}varstein},
  journal={Molecular Microbiology},
  year={2014},
  volume={94}
}
Staphylococcus aureus is a major human pathogen. Hospital infections caused by methicillin‐resistant strains (MRSA), which have acquired resistance to a broad spectrum of antibiotics through horizontal gene transfer (HGT), are of particular concern. In S. aureus, virulence and antibiotic resistance genes are often encoded on mobile genetic elements that are disseminated by HGT. Conjugation and phage transduction have long been known to mediate HGT in this species, but it is unclear whether… Expand
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