Staphylococcus aureus clumping factor B (ClfB) promotes adherence to human type I cytokeratin 10: implications for nasal colonization.

@article{OBrien2002StaphylococcusAC,
  title={Staphylococcus aureus clumping factor B (ClfB) promotes adherence to human type I cytokeratin 10: implications for nasal colonization.},
  author={Louise M O'Brien and Evelyn J. Walsh and Ruth C Massey and Sharon J Peacock and T. J. Foster},
  journal={Cellular microbiology},
  year={2002},
  volume={4 11},
  pages={759-70}
}
Staphylococcus aureus is an important cause of sepsis in both community and hospital settings, a major risk factor for which is nasal carriage of the bacterium. Eradication of carriage by topical antibiotics reduces sepsis rates in high-risk individuals, an important strategy for the reduction of nosocomial infection in targeted patient populations. Understanding the mechanisms by which S. aureus adheres to nasal epithelial cells in vivo may lead to alternative methods of decolonization that do… CONTINUE READING

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