Staphylococcus aureus capsular polysaccharide type 5 conjugate and whole cell vaccines stimulate antibody responses in cattle.

@article{Tollersrud2001StaphylococcusAC,
  title={Staphylococcus aureus capsular polysaccharide type 5 conjugate and whole cell vaccines stimulate antibody responses in cattle.},
  author={Tore Tollersrud and Lillian Zernichow and S. R. Andersen and Kevin B. Kenny and Arve Lund},
  journal={Vaccine},
  year={2001},
  volume={19 28-29},
  pages={3896-903}
}
Dairy heifers were immunized subcutaneously with one of four different vaccines which contained preparations of Staphylococcus aureus capsular polysaccharide type 5 (CP5) and a mineral oil adjuvant, or received a placebo containing saline and adjuvant. The vaccine containing a CP5-human serum albumin conjugate (CP5-HSA) and the vaccine with formaldehyde inactivated whole cells expressing CP5, both elicited strong anti-CP5 antibody responses. After two injections three weeks apart and a third… CONTINUE READING