Staphylococcus aureus biofilms promote horizontal transfer of antibiotic resistance.

Abstract

Growth as a biofilm facilitates the emergence of antibiotic resistance by mutation in Staphylococcus aureus. Here we demonstrate that biofilm growth of this species also dramatically increases horizontal transfer of plasmid-borne antibiotic resistance determinants by conjugation/mobilization and that standard laboratory practices to induce conjugation in… (More)
DOI: 10.1128/AAC.02008-12

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