Staphylococcus aureus alpha-toxin. 1. Effect on protein phosphorylation in myelin.


It has previously been demonstrated that staphylococcal alpha-toxin can selectively induce disruption of myelin sheaths in the central nervous system, albeit the exact mechanism is not known. In this report we show for the first time that the staphylococcal alpha-toxin could stimulate the endogenous phosphorylation of several proteins, including myelin… (More)


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