Staphylococcus aureus alpha-toxin induces apoptosis in endothelial cells.

@article{Menzies2000StaphylococcusAA,
  title={Staphylococcus aureus alpha-toxin induces apoptosis in endothelial cells.},
  author={Barbara E Menzies and I Kourteva},
  journal={FEMS immunology and medical microbiology},
  year={2000},
  volume={29 1},
  pages={
          39-45
        }
}
The internalization of Staphylococcus aureus by cultured human umbilical vein endothelial cells was recently shown to induce apoptosis. We examined the role of alpha-toxin, a major pore-forming toxin secreted by S. aureus, in causing apoptosis in vitro. Purified alpha-toxin, at sublytic concentrations, induced apoptosis in endothelial cell monolayers. Comparisons of two alpha-toxin (hla)-positive S. aureus strains and their isogenic hla-deficient mutants in the invasion assay of endothelial… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 43 extracted citations

Vip3Aa induces apoptosis in cultured Spodoptera frugiperda (Sf9) cells.

Toxicon : official journal of the International Society on Toxinology • 2016
View 2 Excerpts

Similar Papers

Loading similar papers…