Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions

@inproceedings{Mder2016StaphylococcusAT,
  title={Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions},
  author={Ulrike M{\"a}der and Pierre Nicolas and Maren Depke and Jan Pan{\'e}-Farr{\'e} and Michel D{\'e}barbouill{\'e} and Magdalena M. van der Kooi-Pol and Cyprien Guerin and Sandra D{\`e}rozier and Aur{\'e}lia Hiron and Hanne Jarmer and Aur{\'e}lie Leduc and Stephan Michalik and Ewoud Reilman and Marc Schaffer and Frank Schmidt and Philippe Bessi{\`e}res and Philippe Noirot and Michael Hecker and Tarek Msadek and Uwe V{\"o}lker and Jan Maarten van Dijl},
  booktitle={PLoS genetics},
  year={2016}
}
Staphylococcus aureus is a major pathogen that colonizes about 20% of the human population. Intriguingly, this Gram-positive bacterium can survive and thrive under a wide range of different conditions, both inside and outside the human body. Here, we investigated the transcriptional adaptation of S. aureus HG001, a derivative of strain NCTC 8325, across experimental conditions ranging from optimal growth in vitro to intracellular growth in host cells. These data establish an extensive… CONTINUE READING
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