Staphylococcus aureus NrdH redoxin is a reductant of the class Ib ribonucleotide reductase.

@article{Rabinovitch2010StaphylococcusAN,
  title={Staphylococcus aureus NrdH redoxin is a reductant of the class Ib ribonucleotide reductase.},
  author={Inbal Rabinovitch and Michaela Yanku and Adva Yeheskel and Gerald Cohen and Ilya Borovok and Yair Aharonowitz},
  journal={Journal of bacteriology},
  year={2010},
  volume={192 19},
  pages={4963-72}
}
Staphylococci contain a class Ib NrdEF ribonucleotide reductase (RNR) that is responsible, under aerobic conditions, for the synthesis of deoxyribonucleotide precursors for DNA synthesis and repair. The genes encoding that RNR are contained in an operon consisting of three genes, nrdIEF, whereas many other class Ib RNR operons contain a fourth gene, nrdH, that determines a thiol redoxin protein, NrdH. We identified a 77-amino-acid open reading frame in Staphylococcus aureus that resembles NrdH… CONTINUE READING

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