Stannous chloride-induced increase in calcium entry into motor nerve terminals of the frog.

@article{Hattori1989StannousCI,
  title={Stannous chloride-induced increase in calcium entry into motor nerve terminals of the frog.},
  author={Toshimi Hattori and Hiroshi Maehashi},
  journal={European journal of pharmacology},
  year={1989},
  volume={166 3},
  pages={527-30}
}
The effects of SnCl2 on potentials recorded extracellularly from motor nerve terminals of the bullfrog were studied to elucidate the mechanism of the SnCl2-induced facilitation of evoked transmitter release. Under conditions in which the muscle preparations were pretreated with d-tubocurarine and tetraethylammonium in a K+-free medium, SnCl2 (50 microM) augmented the prolonged positive deflection ascribed to the inward Ca2+ current, an effect which was reduced by addition of Cd2+. The results… CONTINUE READING