Standardized test for anti-Tr/DNER in patients with paraneoplastic cerebellar degeneration


OBJECTIVE To determine sensitivity and specificity of a standardized recombinant cell-based indirect immunofluorescence assay (RC-IFA) for anti-Tr antibodies in comparison to a reference procedure. METHODS Delta/Notch-like epidermal growth factor-related receptor (DNER) was expressed in HEK293 and used as a substrate for RC-IFA. HEK293 control cells… (More)
DOI: 10.1212/NXI.0000000000000068


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@inproceedings{Probst2015StandardizedTF, title={Standardized test for anti-Tr/DNER in patients with paraneoplastic cerebellar degeneration}, author={Christian Probst and Lars Komorowski and Esther de Graaff and Marleen H. van Coevorden-Hameete and V{\'e}ronique Rogemond and J{\'e}r{\^o}me Honnorat and Lidia Sabeter and Francesc Graus and Sven Jarius and Raymond Voltz and Brigitte T. Wildemann and Diego Franciotta and Inga Madeleine Bl{\"{o}cker and Wolfgang Schlumberger and Winfried Stoecker and Peter A. E. Sillevis Smitt}, booktitle={Neurology(R) neuroimmunology & neuroinflammation}, year={2015} }