Standardized methods to generate mock (spiked) clinical specimens by spiking blood or plasma with cultured pathogens.


AIMS To demonstrate standardized methods for spiking pathogens into human matrices for evaluation and comparison among diagnostic platforms. METHODS AND RESULTS This study presents detailed methods for spiking bacteria or protozoan parasites into whole blood and virus into plasma. Proper methods must start with a documented, reproducible pathogen source… (More)
DOI: 10.1111/jam.13082


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