Standardized Profiling of The Membrane-Enriched Proteome of Mouse Dorsal Root Ganglia (DRG) Provides Novel Insights Into Chronic Pain.

@article{Rouwette2016StandardizedPO,
  title={Standardized Profiling of The Membrane-Enriched Proteome of Mouse Dorsal Root Ganglia (DRG) Provides Novel Insights Into Chronic Pain.},
  author={Tom Rouwette and Julia R. Sondermann and Luca Avenali and David G{\'o}mez-Varela and Manuela Schmidt},
  journal={Molecular & cellular proteomics : MCP},
  year={2016},
  volume={15 6},
  pages={2152-68}
}
Chronic pain is a complex disease with limited treatment options. Several profiling efforts have been employed with the aim to dissect its molecular underpinnings. However, generated results are often inconsistent and nonoverlapping, which is largely because of inherent technical constraints. Emerging data-independent acquisition (DIA)-mass spectrometry (MS) has the potential to provide unbiased, reproducible and quantitative proteome maps - a prerequisite for standardization among experiments… CONTINUE READING