Standardization of serum neutralization assay of Japanese encephalitis virus (Nakayama NIH strain) on BHK-21 (Cl-13) cell line.

@article{Singh2015StandardizationOS,
  title={Standardization of serum neutralization assay of Japanese encephalitis virus (Nakayama NIH strain) on BHK-21 (Cl-13) cell line.},
  author={Satyapriya Singh and Mona Sharma and Sandeep Kumar and Dipa Gowal},
  journal={Acta virologica},
  year={2015},
  volume={59 3},
  pages={234-9}
}
Potency testing of Japanese encephalitis (JE) vaccine has been a complex process since its inception. To overcome difficulties encountered therein, an alternative assay, serum neutralization test (SNT), using Baby Hamster Kidney 21 cell line, has been standardized. The antibody response generated against JE vaccine was quantified and the assay was found to… CONTINUE READING