Standardization and analytical goals for glycated hemoglobin measurement.

  title={Standardization and analytical goals for glycated hemoglobin measurement.},
  author={Federica Braga and Mauro Panteghini},
  journal={Clinical chemistry and laboratory medicine},
  volume={51 9},
Glycated hemoglobin (HbA1c) plays a key role in diagnosing diabetes and monitoring the glycemic state. To guarantee the reliability of its measurement at the global level, the IFCC has defined a reference measurement system, based on the definition of the measurand as hemoglobin molecules having a special hexapeptide in common, which is the stable adduct of glucose to the N-terminal valine of the hemoglobin β-chain. In addition to the traceability of HbA1c results to the reference system, the… CONTINUE READING

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