Standardising the Lactulose Mannitol Test of Gut Permeability to Minimise Error and Promote Comparability

@inproceedings{Sequeira2014StandardisingTL,
  title={Standardising the Lactulose Mannitol Test of Gut Permeability to Minimise Error and Promote Comparability},
  author={Ivana R Sequeira and Roger G Lentle and Marlena C Kruger and Roger D. Hurst},
  booktitle={PloS one},
  year={2014}
}
BACKGROUND Lactulose mannitol ratio tests are clinically useful for assessing disorders characterised by changes in gut permeability and for assessing mixing in the intestinal lumen. Variations between currently used test protocols preclude meaningful comparisons between studies. We determined the optimal sampling period and related this to intestinal residence. METHODS Half-hourly lactulose and mannitol urinary excretions were determined over 6 hours in 40 healthy female volunteers after… CONTINUE READING
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