Standard operating procedures for pre-analytical handling of blood and urine for metabolomic studies and biobanks.

@article{Bernini2011StandardOP,
  title={Standard operating procedures for pre-analytical handling of blood and urine for metabolomic studies and biobanks.},
  author={Patrizia Bernini and Ivano Bertini and Claudio Luchinat and Paola Nincheri and Samuele Staderini and Paola Turano},
  journal={Journal of biomolecular NMR},
  year={2011},
  volume={49 3-4},
  pages={231-43}
}
(1)H NMR metabolic profiling of urine, serum and plasma has been used to monitor the impact of the pre-analytical steps on the sample quality and stability in order to propose standard operating procedures (SOPs) for deposition in biobanks. We analyzed the quality of serum and plasma samples as a function of the elapsed time (t = 0-4 h) between blood collection and processing and of the time from processing to freezing (up to 24 h). The stability of the urine metabolic profile over time (up to… CONTINUE READING

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