Stammzellgestützte Hochdosischemotherapie (HDC) des Ovarialkarzinoms
@article{Nitz1997StammzellgesttzteH, title={Stammzellgest{\"u}tzte Hochdosischemotherapie (HDC) des Ovarialkarzinoms}, author={U. Nitz}, journal={Der Gyn{\"a}kologe}, year={1997}, volume={30}, pages={126-132} }
Zum ThemaWegen der hohen Chemotherapiesensibilität der Ovarialkarzinome erscheint eine Verbesserung der Überlebensraten durch hochdosierte Chemotherapeutika möglich. Die Dosiseskalation ist in der Regel durch die Knochenmarktoxizität limitiert. Die Transplantation autologer hämatopoetischer Stammzellen ermöglicht die Hochdosistherapie, z. B. mit Dreierkombinationen von Alkylantien.Die Gewinnung der aus dem Knochenmark ausgeschwemmten ,,peripheren Stammzellen” erfolgt aus dem peripheren Blut… CONTINUE READING
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