Stalin's Forgotten Cure

  title={Stalin's Forgotten Cure},
  author={Richard A. Stone},
  pages={728 - 731}
  • R. Stone
  • Published 25 October 2002
  • Medicine, Biology
  • Science
TBILISI-- Bacteriophage therapy, pioneered in Stalin-era Russia, is attracting renewed attention in the West as a potential weapon against drug-resistant bugs and hard-to-treat infections. Phages--viruses that infect bacteria--could soon find a role as a treatment for burns, diabetic ulcers, and other open wounds, although experts concur that these viral breeds are unlikely to knock antibiotics off their pedestal for most infections. 

Bacteriophages for managing Shigella in various clinical and non-clinical settings

The control of shigellosis in humans enjoys a prominent position in the history of bacteriophage therapy and the use of phages to control the disease in humans and the spread of the bacteria within food and water could point the way forward to the effective management of an infectious disease with global influence.

New insights into the possible role of bacteriophages in transplantation.

Phage therapy: a reappraisal of bacteriophages as antibiotics.

  • J. Inal
  • Medicine
    Archivum immunologiae et therapiae experimentalis
  • 2003
The potential of phage therapy against bioterrorism and the emergence of second generation phage antibacterials based on phage-derived single-protein lysis systems are addressed.

Bacteriophage therapy: old treatment, new focus?

This article will examine some of the recent developments and obstacles in the field of bacteriophage therapy.

Bacteriophage therapy--cooked goose or phoenix rising?

Bacteriophage Therapy: A possible new alternative for oral diseases

Phage therapy, a method using phages for the treatment of bacterial infectious diseases was introduced by Felix D Herelle in 1920, but with the arrival of the the antibiotic era in the 1940 s it got suppressed, but the ongoing evolution of bacterial multidrug resistance, the potential of phage therapy is again being evaluated.

Phage Therapy and the Future

Phage therapy is actively being investigated as a treatment to prevent food spoilage, and as a veterinary medicine, and the time is ripe to begin phage therapy clinical trials in the West because of the high risk of antibiotic-resistant strains of bacteria.

Phage therapy of staphylococcal infections (including MRSA) may be less expensive than antibiotic treatment.

Data is presented showing that efficient phage therapy of staphylococcal infections is no longer a treatment of last resort (when all antibiotics fail), but allows for significant savings in the costs of healthcare.

Potential duel-use of bacteriophage related technologies in bioterrorism and biodefense.

The potential for bacteriophages to be used as bioterrorism agents or tools, as well as in counter-measures against biot errorism, is described.

Enzybiotics: The Rush Toward Prevention and Control of Multiresistant Bacteria (MRB)

The search for phage-based products to use in pharmaceutical formulations opens a new window of hope for medicine in the struggle against illness currently resistant to antibiotic treatment, since new anti- biotic-resistant strains are emerging at a constant rate.