Staining of glial fibrillary acidic protein (GFAP) in lumbar spinal cord increases following a sciatic nerve constriction injury

@article{Garrison1991StainingOG,
  title={Staining of glial fibrillary acidic protein (GFAP) in lumbar spinal cord increases following a sciatic nerve constriction injury},
  author={C. Garrison and P. Dougherty and K. Kajander and S. Carlton},
  journal={Brain Research},
  year={1991},
  volume={565},
  pages={1-7}
}
  • C. Garrison, P. Dougherty, +1 author S. Carlton
  • Published 1991
  • Medicine
  • Brain Research
  • The change in staining density of glial fibrillary acidic protein (GFAP) was analyzed in rats that sustained a chronic constriction injury produced by sutures tied loosely around one sciatic nerve. This injury model of peripheral neuropathy resulted in a behavioral hyperalgesia evidenced by a decrease in mean foot withdrawal latency to radiant heat. Increased GFAP immunostaining was observed in the gray matter of the spinal cord ipsilateral to the lesion and specific to spinal segments in which… CONTINUE READING
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