Staging of endometrial cancer with MRI: Guidelines of the European Society of Urogenital Imaging

Abstract

The purpose of this study was to define guidelines for endometrial cancer staging with MRI. The technique included critical review and expert consensus of MRI protocols by the female imaging subcommittee of the European Society of Urogenital Radiology, from ten European institutions, and published literature between 1999 and 2008. The results indicated that high field MRI should include at least two T2-weighted sequences in sagittal, axial oblique or coronal oblique orientation (short and long axis of the uterine body) of the pelvic content. High-resolution post-contrast images acquired at 2 min ± 30 s after intravenous contrast injection are suggested to be optimal for the diagnosis of myometrial invasion. If cervical invasion is suspected, additional slice orientation perpendicular to the axis of the endocervical channel is recommended. Due to the limited sensitivity of MRI to detect lymph node metastasis without lymph node-specific contrast agents, retroperitoneal lymph node screening with pre-contrast sequences up to the level of the kidneys is optional. The likelihood of lymph node invasion and the need for staging lymphadenectomy are also indicated by high-grade histology at endometrial tissue sampling and by deep myometrial or cervical invasion detected by MRI. In conclusion, expert consensus and literature review lead to an optimized MRI protocol to stage endometrial cancer.

DOI: 10.1007/s00330-009-1309-6

6 Figures and Tables

0200400600800200920102011201220132014201520162017
Citations per Year

2,036 Citations

Semantic Scholar estimates that this publication has 2,036 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Kinkel2009StagingOE, title={Staging of endometrial cancer with MRI: Guidelines of the European Society of Urogenital Imaging}, author={Karen Kinkel and Rosmarie Forstner and Francesco M. Danza and Laura Oleaga and Teresa Margarida Cunha and Arik Bergman and Jelle O. Barentsz and Corinne Balleyguier and Boris Brklja{\vc}i{\'c} and John David Spencer}, journal={European Radiology}, year={2009}, volume={19}, pages={1565-1574} }